The Joye of Snacks Science

The Joye of Snacks Science

To all aspiring young scientists who might be reading this blog post, if you’re considering a career in science that involves doing a PhD, let me tell you this – when someone uses the phrase ‘wedded to your work’ – they mean it in as literal a manner as possible, given that your work isn’t actually a real person and your relationship isn’t officially recognized (however if you’re lucky you do get a certificate, and unlike other forms of marriages that aren’t recognized, you’re lauded and not ostracized). I just feel like one of those couples who go through a tough time after a long marriage but rediscover the flame after a second honeymoon.. Three years into grad school and just as short a while ago as the beginning of this summer, I felt like I’d had just about enough and was ready to quit. This is not a good place to be if you recognize that you are, at the very most, about halfway into your PhD. A combination of circumstances managed to turn this train around, of which two conversations stand out in my memory of the past few weeks.

The first is a conversation with my prof. For all that he now seems to me like the busiest person on the planet, I still do meet him every other week for half an hour of very inspiring quality time. About a month ago, I was not only half an hour late for this conversation with no good reason (I forgot it was a Friday) but I also nearly broke down and cried. To his credit, Prof simply ignored the crying part and instead asked me what my goals were. “To get a PhD,” I sniffled miserably. While this seemed like a perfectly reasonable goal before, at the end of that conversation I realized that it wasn’t, and in fact was just my problem – I’d got so sucked up into the act of doing things required to keep me in the program that would get me a PhD that I forgot why I chose to get it in the first place! This answer might be different for everyone. A lot of people who commit to science may do it for the excitement of discovery, or out of the desire to improve our knowledge of the natural world, to contribute to medical breakthroughs and so on. Me – I came in to learn. The most attractive thing about the whole grad school program for me was that I’d be getting paid to learn and as a PhD student, there’s no pressure to make major scientific discoveries and earn grants, but if you demonstrate that you have a solid knowledge of the background and the practical work in your field, as well as critical thinking ability and presentation skills which you’re expected to learn by going through the program and not necessarily before you begin, your PhD is considered a success.

I also came to play. Which brings me to the second encounter. Anyone who’s remotely interested in Science should find a way of talking to Dr. Kim Kelly. And anyone who thinks hardcore science is no fun should also talk to her. She has all the explosive energy of an atom bomb and all the enthusiasm of the most bubbly cheerleader of your acquaintance (come to think of it, she may have been a cheerleader once..). And she’s making a big splash with her science. Talking to her reminded me that my enthusiasm levels in general were flagging.

Plus, almost word for word, she reiterated what Prof said the previous week – the biggest failure is to never try.

And finally, this is addressed to any jaded grad students who might also be reading my post and rolling their eyes. Here’s a (hard) lesson I learnt from a senior ballet teacher who’s a dragon on the outside and a treasure on the inside.. if it hurts, smile wider.

Something to remember when you drop an experiment that took you two weeks and 700 dollars to do.

Mrs. Beeton’s Textbook of Biology

Mrs. Beeton’s Textbook of Biology

I’ll admit I bought a copy of Mrs. Beeton’s on a whim, having come across it in so many contexts. The book’s quite a piece of work, and so’s Mrs. B! Quite apart from her extensive recipe section, she has information on behaviour/etiquette, the care of children, management of financial affairs and domestic help, first-aid at home, legal advice – and the parts that impressed me the most – The natural history of birds, beasts, fish, vegetables and other edible things I may not have included on that list. She has illustrations of the microscopic view of plant stem cross-sections and descriptions of the mechanics that allow a bird to fly. And I always thought it was just a cookbook!

Sometime in the future when I figure out how much of the book I can include here without infringing copyright, I’ll show you what I mean.

 

One Game to End Them All.

One Game to End Them All.

So.. I have been trying to wean myself off of Facebook entirely and move over to Google+, because all I do on Facebook is stalk people and play games.. I don’t actually post anything on there :P Unfortunately, Zynga has been the bane of my life – how can I ignore my poor Frontier chickies when they’re clucking away every half hour demanding to be fed? Or resist expanding my pretty city with its fountains and peaceful housing communities by the zoo? Or keep from digging treasure on exotic islands? Or learn the colourful new recipes that Playfish’s Restaurant keeps putting out?

I think I’ve made my point.

My temporary solution has been to take on an all-consuming game that is inherently limited (ok, so I didn’t choose the limited part, it just happened to be the only thing playable on a mac..) and so I’ve signed myself up for WoW, the trial version. I’ve already leveled one character to the trial cap – don’t know if I’m allowed to play her for longer only without gaining experience, or if I’ll be kicked off the server sometime soon. But there you go – I can’t play longer than an hour a day because frankly I care about my shiny new macbook pro (she’s named Saya, btw) heating up more than I care for the game, and an hour a day of roleplaying in a realistic environment leaves me with no particular desire to shift cartoon houses or horses around in Flash.

I rather like this setup, methinks XD

African Flowers 8-petal version, picture tutorial.

African Flowers 8-petal version, picture tutorial.

This pattern is something I’ve found fascinating for quite a while. The original is made in hexagonal format with a 6-petal flower per unit. This 8-petal format is useful for making squares, Crafty Bees at the Q*Bee might find this useful :)
This is a step-by-step picture tutorial based off of this pattern.

( If you don’t see pictures yet, it’s because I’m in the process of crocheting it :) )

1. Make a ring – either using the ‘magic loop’ method, or the more standard method of chaining 7 and joining the last chain with the first chain using a slip stitch.

2. chain 2 (this counts as the first double-crochet or dc) dc once into the ring, chain one. [set 1]


dc twice into the ring and chain one. [set 2]
dc twice into the ring and chain one. [set 3]
dc twice into the ring and chain one. [set 4]
dc twice into the ring and chain one. [set 5]
dc twice into the ring and chain one. [set 6]
dc twice into the ring and chain one. [set 7]
dc twice into the ring and chain one. [set 8]
Join this last with the first ‘dc’ (which was the chain-2)

3. Make a slip-stitch into the neighbouring ‘chain one’ space from previous round.


Chain 2 (counts as first dc). dc into the same ‘chain one’ space from previous round. Chain one and 2 dc into the same ‘chain one’ space from previous round. [set 1]


2 dc into the next ‘chain one’ space from previous round. chain one, 2dc into same chain one space. [set 2]
2 dc into the next ‘chain one’ space from previous round. chain one, 2dc into same chain one space. [set 3]
2 dc into the next ‘chain one’ space from previous round. chain one, 2dc into same chain one space. [set 4]
2 dc into the next ‘chain one’ space from previous round. chain one, 2dc into same chain one space. [set 5]
2 dc into the next ‘chain one’ space from previous round. chain one, 2dc into same chain one space. [set 6]
2 dc into the next ‘chain one’ space from previous round. chain one, 2dc into same chain one space. [set 7]
2 dc into the next ‘chain one’ space from previous round. chain one, 2dc into same chain one space. [set 8]
Join with slip stitch into first ‘dc’ (which was a chain-2)

4. Slip-stitch into next dc from previous round. slip-stitch into ‘chain one’ space from previous round.


chain 2 (counts as first dc), 6 more dc in the same chain one space [set 1]

dc into the next ‘chain one’ space from the previous round, 6 more dc into the same ‘chain one’ space. [set 2]

..do the same to get 8 sets of 7dc in each chain one space. Each of these sets of 7 dcs makes a ‘petal’.
Join with slip-stitch into the first dc (which was chain 2).

5. dc straight down into the round before the petal round. slip-stitch into each of the 7 dcs from the first petal of the previous round (see picture) [1]
dc into space between the 2 petals to the space, into the round before the petal round [2]

similarly, slip-stitch into the dcs in each petal and dc into the round before the petal round, between each petal.

join with slip stitch into first dc.

6. slip-stitch into 4 neighbouring dcs (to reach the middle of the petal)


chain 2 (to make the first dc) dc 7 more dcs into each slip stitch from the previous round (8 dcs in a row, until the middle of the next petal) chain one. [makes 1st edge]
again dc 8 in a row into the slip stitches from the previous round [makes 2nd edge]

Continue around until all 8 edges are complete. Join with slip-stitch into first stitch.

7. slip-stitch into 8 dcs from previous round until you reach the first chain one space from the previous round.
[1st corner] 3 treble stitches, 3 chains, 3 treble stitches;
slip-stitch into the next ‘chain one’ space from the previous round. slip-stitch into the next 8 dcs from the previous round.

[2nd corner] 3 treble stitches, 3 chains, 3 treble stitches
slip-stitch into the next ‘chain one’ space from the previous round. slip-stitch into the next 8 dcs from the previous round.

Similarly, finish the other 2 corners, and join with a slip-stitch into first stitch.

Fin!

Book Meme

Book Meme

Speaking of reading…

I answered a book meme on Q*bee’s bookworms club. Re-posting here :)

1. What is your favorite genre to read? Why?
Classics and Fantasy – both for the same reason – I like to escape into other worlds and often of a slower pace.

2. Do you have a favorite author? If so, who is it?
At the moment, it’s Terry Pratchett. Other favourites have been Elizabeth Gaskell, L.M. Alcott, Jane Austen, Arthur Conan Doyle, Ruskin Bond, J.K. Rowling, J.R.R. Tolkien.

3. Why do you like to read?
See 1. :) Also, I like getting perspective on how other minds can think – living someone else’s life through a story provides that.

4. Do you tend to reread your favorite books over and over again or is one time enough no matter how well you liked the book?
I do re-read my favourites, but I like to do that after a long gap (sometimes years).

5. Approximately how many books do you read a read? (ball park guess is fine)
I go months without reading, and then do several books a week. This year I’ve read ~25 books, might get some more through before the year is done. Last year after getting my Nook (July end) I went through about the same number :mellow:


					

New Site!

New Site!

Friends from the Q*bee!

So.. after about 3 years of an underused paid domain (bought it just so I could set up MyQuiltAdmin – somehow never got it to work and wasn’t motivated enough to troubleshoot it), I have decided to switch over to here. It’s pretty, hassle-free and, well, just plain free!

Just to let you know what to expect here, I will be continuing the science blogging I’d started up on my old site (for those who’ve noticed the solitary post).

That’s about it for now!

4 exclamation marks already.. I might as well break into a Kwesta??! Maladetta?!?! :D

Epigenetics and the Mother’s Day Song

Epigenetics and the Mother’s Day Song

Watch the Video

Ever since this came out on Mother’s Day this year, I’ve been rather hooked. As someone who works in a lab where more than half of the members study epigenetic inheritance, I’m able to appreciate much of the content (in fact, one recent mom opened her lab meeting presentation with this video). Watch it, and you’ll learn it’s not BS but absolutely true…

Genetic Inheritance

Most of us have heard about DNA and genes that we inherit from our biological parents, and how they’re responsible for everything from development to disease. Genes in the DNA encode (for the most part) proteins, which are the machines that are responsible for almost every biological function we know of (incidentally, this is why it’s a good idea to include a lot of protein in your diet, so that your body can break them down and reuse the components to make more of its own protein). Variants of the same gene, called ‘alleles’, can occur in different people. Eye colour, blood type and propensity to a number of diseases are determined by which allele of the responsible genes you have.

How the Environment Affects Genes

It’s not always enough to just have the gene, however. Environmental factors such as temperature, nutrition, interaction and even where the foetus was positioned during pregnancy all appear to have an effect on different traits given the exact same genetic background (i.e. identical genes). While we don’t always understand what these external factors are and the mechanism by which they function to change gene expression, we can look at how the DNA has changed while its sequence stays the same.

Changing DNA Without Changing its Sequence

DNA is a molecule, and it can undergo chemical changes. It is made up of building-blocks called nucleic acids, which are strung together in a particular sequence. This sequence of the 4 nucleic acids that make up DNA (A, T, C and G) is what contains the genetic information. DNA is also associated with proteins called histones that help organize the DNA within the cell. Both the DNA molecule and the Histone proteins can be chemically modified at select locations by enzymes in the cell. This essentially makes that particular region along the molecule look different than its surroundings. The modifications can therefore function as ‘flags’ or signals to other enzymes that are involved in the expression of genes, telling them, in a way, what they’re supposed to do.

Nearly Everything that Matters..

How this is all connected to the Mother’s Day song is – it is not really known when exactly these instructions are first laid down, and how the cell knows exactly where and when to do so. There is some evidence to show that much of the poising happens in the embryo and foetus during development, and perhaps before fertilization. To extrapolate, what Mom tells her eggs to do even before they’ve been fertilized to form an embryo, could potentially have an effect much, much later in development when Baby is actually born!

“I got so much more from you mom
Than just half a set of genes”

I’ll say!